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Assistant professor in stem cell biology in the Jensen group

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An assistant professor position in intestinal stem cell biology is available for a highly motivated and independent scientist in the Jensen Group at BRIC, University of Copenhagen

The focus of our research is to understand how tissue establishes mechanisms that control homeostasis during development and in adult tissues. We study the epithelial components of the skin and the intestine, as they both need constant replenishment throughout life from resident stem cells (Jensen et al., 2009, Cell Stem Cell; Wong et al., 2012, Nature Cell Biology; Page et al., 2013, Cell Stem Cell; Fordham et al., 2013, Cell Stem Cell). Here we use a number of different techniques including in vivo fate mapping and state of the art cell culture systems in order to define cellular heritage and identify signalling pathways important for normal cell behaviour. Insights into the development processes leading to the formation of a normal epithelium will have widespread implications on regenerative medicine and in vitro disease modelling.

The project
Analysis of the maturing intestinal epithelium in neonatal tissue samples from both mouse and human foetuses has enabled us to identify a distinct population of foetal intestinal progenitors. These progenitors can be maintained in culture without spontaneously maturing into their adult counterparts (Fordham et al., 2013, Cell Stem Cell). We have characterised both foetal and adult populations extensively and identified a number of differentially expressed key transcription factors. This served as the starting point for the successful candidate to investigate how adult intestinal stem cells can be derived from both human and mouse foetal and pluripotent sources. Previous experience with handling pluripotent and somatic stem cells as well as transcriptional regulation is advantageous.

Start: December 2015 or after agreement
Duration: 2 years

Please read more about the Jensen research group and BRIC on www.bric.ku.dk

Qualifications
We expect you to be a highly motivated and ambitious scientist with the following qualifications:

  • A PhD in Life Sciences
  • Documented experience in stem cell biology is required
  • Prior experience in analysis of animal models and stem cell models is advantageous
  • A strong background in molecular and cellular biology
  • Excellent technical skills
  • Excellent English skills written and spoken

For further information regarding the position, please contact Associate Professor Kim Jensen on kim.jensen@bric.ku.dk

Place of employment
The employment is at BRIC, University of Copenhagen. BRIC is located in the Biocenter, close to the centre of Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include modern laboratories and a number of core facilities shared between the 23 research groups at BRIC and the neighboring Finsen Laboratory. We have weekly journal clubs, data clubs, seminars with invited speakers and a young researchers club ASAP and our own PhD programme, MoMeD. BRIC actively participates in the European alliance, EU-life consisting of 13 excellent life science research institutions http://www.eu-lide.eu/.

Terms of salary and employment
Salary, pension and terms of employment will be in accordance with the agreement between the Ministry of Finance and The Academics Central organization. Currently, the monthly salary starts around 32.095 DKK/ca. 4.250 Euro plus pension. Depending on qualifications, a higher salary may be negotiated.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013.

Application
Your application must be submitted electronically by clicking ‘Apply now’ below or via BRIC’s website on http://www.bric.ku.dk/jobs/. The application must include the following documents/attachments – all in PDF format:

 

  1. Motivated letter of application (max. one page).
  2. CV incl. education, work/research experience, language skills and other skills relevant for the position.
  3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
  4. List of publications.

Letters of recommendation
Furthermore, the applicant should provide two letters of recommendation. To be taken into consideration, the letters must be signed by the supporting persons on paper with institutional letter head and in PDF-format. They should be sent before deadline to jobs@bric.ku.dk with subject “Jensen-AssistProf-Dec2015”; preferably by the supporting persons. Please make sure that an easy match between the recommendation letter and the individual applicant is possible.

Application deadline: 8 November 2015.

We reserve the right not to consider material received after the deadline, and not to consider applications or letters of recommendation that do not live up to the above-mentioned requirements.

The further process
Shortlist: After expiry of the application deadline, the superior with power to appoint selects a number of applicants for assessment on the advice of the Appointments Committee. All applicants are immediately notified whether their application has been passed for assessment. Applicants who were not passed for assessment should not expect further with regard to their application unless the shortlist is revised.

Assessment: The selected applications will be assessed according to the Ministry Order on the Appointment of Academic Staff at Universities 2012 and the University of Copenhagen’s guidelines 2013. The Assessment Committee makes a non-prioritized assessment of the academic qualifications and experience with respect to the above mentioned area of research, techniques, skills and other requirements listed in the advertisement.

You can read about the recruitment process at http://employment.ku.dk/faculty/

 BRIC and University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.

EOJD